Osteoarthritis Knee: To Run or Not? Evidence-Based Answers

Posted by Bharath Mark (M7LW) October 16th, 2025

Running with Knee Osteoarthritis

Is the World at Its Knees?

In 2019, about 528 million people worldwide were diagnosed with Osteoarthritis (OA); an increase of 113% since 1990. As life expectancy is improving worldwide, the population is currently feeling weak at the knee. About 73% of people living with OA are older than 55 years, and 60% are female.

With a prevalence of 365 million, the knee is the most frequently affected joint, followed by the hip and the hand (Long H et al, 2022).

The Growing Burden of OA Knee

As the burden of OA knee is rising significantly, the incidences of knee arthritis among Indians is believed to be up to 15 times higher than that found in Western nations. More than 150 million Indians suffer from knee problems, out of which forty million need a total knee replacement (TKR), imposing a huge health burden on the society and country. In contrast, China has 65 million people who suffer from OA knee, which is less than half the number in India. The prevalence of OA knee is more in Indian women than men due to post menopausal issues (Thati 2021).

The Common Belief About Running and Arthritis

There is a strong belief that arthritis can affect runners knee, and it is believed that running is a primary cause of arthritis. This article focuses on OA knee and effects of running with the recent evidence available to date.

American College of Sports Medicine (ACSM) currently recommends that healthy adults aged 18 to 65 need to participate in 150 minutes of moderate intensity aerobic physical activity five days a week or vigorous intensity aerobic activity for a minimum of 20 minutes on three days per week. Running is a great form of cardiovascular exercise that helps achieve the goals to stay fit.

There is a significant perception in our community including health practitioners that running can cause irreversible damage and degeneration of knee, accelerating early onset of OA. In addition, patients with OA knee are advised to refrain from running.

Common Questions from Patients

The following are few important questions and thoughts from patients that health practitioners come across regarding running:

  1. Can I end up worsening my knees condition?
  2. Am I at greater risk to suffer from OA knee compared to runners?
  3. Isn't it unwanted strain and stress to the knee joint if I run?
  4. I think I should save my knee for my old age by not running or play too much of sports
  5. The most crucial question – I cannot run because I have an arthritis!

What Does the Evidence Actually Say?

However, this is not completely true. On the contrary to answer these questions, mounting evidence which are investigating similar queries for decades have come closer to understanding the issue. Few of the key evidence suggests the following:

  • A short term follow up study (Dhillon et al 2023) has shown running is not associated with worsening of patient reported outcome or radiological signs of OA knee.
  • A recent analysis of 24 studies (CoBurn 2022) found no evidence of significant harm to the cartilage lining the knee joints on MRIs taken just after single bout of running.
  • There is no progression of osteoarthritis (on imaging) over an 18 year period in long distance runners.
  • A study looked at trained and untrained marathon runners knee MRI. Interestingly, there was no significant risk of injuries. In fact the bone mineral density improved and no worsened knee pain related to arthritic changes.
  • A study published in 2017 found that recreational runners had lower rates of hip and knee OA (3.5%) compared with competitive runners (13.3%) and nonrunners (10.2%). This study shows there is negligible difference in Osteoarthritis in those who run vs. those who don't run.

Key Take-Home Messages:

  1. Running is not a likely cause of OA knee. In fact running can be protective and maintain joint health.
  2. Running is awesome and add this activity to reduce the mortality rate by up to 30%
  3. Does not necessarily worsen your arthritic condition and pain.
  4. The strongest factors associated to progression of Knee arthritis is obesity and previous knee trauma.

Conclusion

In conclusion, there is moderate to low evidence that suggests running is a safe sport that can be added into your daily activity. There is greater benefit in running which outweighs potential harm. In addition, it does not show any considerable risk of degeneration and injuries to the knee.

A Word for Physiotherapists

This is a call for physiotherapists to bear the responsibility in guiding the client through the stages to accomplish the objective. To develop a specific rehab plan is critical in effectively managing the OA knee. This can be attained only through thorough assessment of the client and addressing specific issues which is the key factor in achieving the desired goal. The sound knowledge of specific strength & conditioning principles is very important.

Failure in improper assessment, Management and lack of knowledge will result in clients receiving generalized, underdosed and non specific exercise program that does not improve their symptoms. In contrast, it can lead to detrimental effects on a knee.

Expert Assessment and Management at M7LW

At M7 Lifestyle & Wellness, we take a comprehensive, evidence-based approach to OA knee management:

  • Thorough Assessment: Detailed evaluation of your condition, pain patterns, and functional goals
  • Individualized Exercise Prescription: Tailored programs based on your specific needs and lifestyle
  • Evidence-Based Strategies: Incorporation of the latest research into your treatment plan
  • Strength & Conditioning: Specific training principles to support joint health
  • Education & Empowerment: Understanding your condition and how to manage it effectively

📍 Visit us at M7LW, Anna Nagar, Chennai, or reach out to schedule an appointment with Bharath Mark for comprehensive OA knee assessment and management.

About the Author

Bharath Mark
Lifestyle Medicine Advocate (Harvard Medical School, Boston)
MS Manual & Sports Physiotherapist (Adelaide)
MHSc Exercise Prescription, Hand injury & Biomechanics Specialist (Sydney)
B Physio

References

  • GBD 2019: Global burden of 369 diseases and injuries in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019.
  • Chakravarty E.F. 2008. "Long Distance Running and Knee Osteoarthritis: A Prospective Study". American Journal of Preventive Medicine. 35(20); pp 133-138
  • Co Burn S.L., Crossely K.M., Kemp J.L., Bruder A.M., Mentiplay B.F., Culvenor A.G. 2022: "Is running good or bad for your knees? A systematic review and meta-analysis of cartilage morphology and composition changes in the tibiofemoral and patellofemoral joints". Osteoarthritis and Cartilage. 31 (2); pp144- 157.
  • Lane NE, Michel B, Bjorkengren A, et al. 1993 "The risk of osteoarthritis with running and aging: a 5-year longitudinal study". Journal of Rheumatology. 20: pp 461-468.
  • Lo GH, Driban JB, Kriska AM, et al. 2017. "Is There an Association Between a History of Running and Symptomatic Knee Osteoarthritis? A Cross-Sectional Study From the Osteoarthritis Initiative". Arthritis Care Res (Hoboken). 69(2): pp 183–191
  • Long H, Liu Q, Yin H, Diao N, Zhang Y, Lin J et al. Prevalence trends of site-specific osteoarthritis from 1990 to 2019: Findings from the global burden of disease study 2019. Arthritis Rheumatol 2022; 74(7): 1172-1183.
  • M.Blagojevic C.Jinks A.Jeffery K.P.Jordan, 2010. "Risk factors for onset of osteoarthritis of the knee in older adults: a systematic review and meta-analysis." Osteoarthritis and Cartilage. 18(1); pp 24-33
  • Thati Srinivas, 2021. Gender differences in Osteoarthritis of knee: An Indian perspective. Journal of Midlife health. 12 (1); pp 16-20.

Ready to Manage Your OA Knee Safely and Stay Active?

Don't let knee pain limit your life. Book your appointment with Bharath at M7LW today and discover how evidence-based assessment and management can help you stay active and pain-free.